Acute Renal Failure due to Leukaemic Infiltration in Chronic Lymphocytic Leukaemia.

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KAYAR Y., EKINCI İ., Bay I., KAYAR N. B., HAMDARD J., Kazancioglu R.

Case reports in medicine, vol.2015, pp.469136, 2015 (Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 2015
  • Publication Date: 2015
  • Doi Number: 10.1155/2015/469136
  • Journal Name: Case reports in medicine
  • Journal Indexes: Scopus
  • Page Numbers: pp.469136
  • Bezmialem Vakıf University Affiliated: Yes


Chronic lymphocytic leukemia (CLL) is a malignancy characterized by clonal proliferation and accumulation of B lymphocytes. Although leukaemic infiltration of the kidney is well recognized in CLL, acute renal failure (ARF) due to leukaemic infiltration is extremely rare. Here we present a case of ARF as the initial manifestation of CLL. The diagnosis was made by a kidney biopsy. Treatment with cyclophosphamide and prednisolone resulted in a completely improved renal function.