Acute Renal Failure due to Leukaemic Infiltration in Chronic Lymphocytic Leukaemia.

Creative Commons License

KAYAR Y., EKINCI İ., Bay I., KAYAR N. B., HAMDARD J., Kazancioglu R.

Case reports in medicine, vol.2015, pp.469136, 2015 (Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 2015
  • Publication Date: 2015
  • Doi Number: 10.1155/2015/469136
  • Journal Name: Case reports in medicine
  • Journal Indexes: Scopus
  • Page Numbers: pp.469136
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

Chronic lymphocytic leukemia (CLL) is a malignancy characterized by clonal proliferation and accumulation of B lymphocytes. Although leukaemic infiltration of the kidney is well recognized in CLL, acute renal failure (ARF) due to leukaemic infiltration is extremely rare. Here we present a case of ARF as the initial manifestation of CLL. The diagnosis was made by a kidney biopsy. Treatment with cyclophosphamide and prednisolone resulted in a completely improved renal function.