The efficacy of a hemostatic agent in anticoagulant drug-induced rat bleeding model

Sonmez, Ertan; ÇAVUŞ, Umut; CİVELEK, Cemil; DUR, Ali; KARAYEL, Eda; Gulen, BEDİA; Uysal, ÖMER; İPEK, Gokturk

doi:10.5505/tjtes.2014.54938

The efficacy of a hemostatic agent in anticoagulant drug-induced rat bleeding model

Sonmez E. , ÇAVUŞ U. Y. , CİVELEK C., DUR A., KARAYEL E., Gulen B. , et al.

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, cilt.20, ss.79-85, 2014 (SCI İndekslerine Giren Dergi)

Cilt numarası: 20 Konu: 2
Basım Tarihi: 2014
Doi Numarası: 10.5505/tjtes.2014.54938
Dergi Adı: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
Sayfa Sayısı: ss.79-85

Özet

BACKGROUND: Bleeding is a major problem in warfarin pretreated patients who need emergency surgical procedures. APH is a hemostatic agent with ultra-hydrophilic and particulate properties. This study aimed to evaluate the in vivo hemostatic effect of APH in rats pretreated with warfarin.