The efficacy of a hemostatic agent in anticoagulant drug-induced rat bleeding model

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Sonmez E., ÇAVUŞ U. Y., CİVELEK C., DUR A., KARAYEL E., Gulen B., ...More

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, vol.20, no.2, pp.79-85, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 2
  • Publication Date: 2014
  • Doi Number: 10.5505/tjtes.2014.54938
  • Journal Name: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.79-85
  • Keywords: Hemostatic, rat, warfarin, MICROPOROUS POLYSACCHARIDE HEMOSPHERES, CUTANEOUS SURGERY, WARFARIN THERAPY, MANAGEMENT, COMPLICATIONS, ANTIPLATELET, ASPIRIN, MPH
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

BACKGROUND: Bleeding is a major problem in warfarin pretreated patients who need emergency surgical procedures. APH is a hemostatic agent with ultra-hydrophilic and particulate properties. This study aimed to evaluate the in vivo hemostatic effect of APH in rats pretreated with warfarin.