Effect of inhaled steroids on clinical and inflammatory parameters in children with cystic fibrosis

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UYAN Z., Unluguzel Ustun G., Haklar G., ÇAKIR E., OKTEM S., ERSU R., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.47, no.5, pp.1432-1440, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 5
  • Publication Date: 2017
  • Doi Number: 10.3906/sag-1509-101
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1432-1440
  • Keywords: Antiinflammatory treatment, children, cystic fibrosis, glucocorticoids, inhalation, RANDOMIZED CONTROLLED-TRIAL, LUNG-FUNCTION DECLINE, FLUTICASONE PROPIONATE, ANTIINFLAMMATORY THERAPIES, AIRWAY INFLAMMATION, YOUNG-CHILDREN, LONG-TERM, CORTICOSTEROIDS, SPUTUM, METHACHOLINE
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

Background/aim: The effectiveness of inhaled corticosteroids (ICSs) in cystic fibrosis (CF) is controversial. The aim of this study was to investigate the effect of an ICS on bronchial hyperreactivity (BHR), oxidative status, and clinical and inflammatory parameters in CF patients.