Expression of miRNA-21, miRNA-107, miRNA-137 and miRNA-29b in meningioma


Katar S., Baran O., Evran S., Cevik S., Akkaya E., Baran G. , ...Daha Fazla

CLINICAL NEUROLOGY AND NEUROSURGERY, cilt.156, ss.66-70, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 156
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.clineuro.2017.03.016
  • Dergi Adı: CLINICAL NEUROLOGY AND NEUROSURGERY
  • Sayfa Sayıları: ss.66-70

Özet

Objective: Meningiomas are among the most common intracranial tumors, accounting for 30% of all tumors of the central nervous system. Recent studies analyzing microRNA (miRNA) profiles and functions in cancer have provided valuable information about the molecular pathogenesis of several tumor types, including glioblastoma multiforme (GBM), hepatocellular carcinoma, and breast, lung, colon, and prostate cancer. miRNAs are a family of small, endogenous, noncoding RNAs of 18-25 nucleotides. In this study, we carried out a genome-wide array screen comparing miRNA-21, miRNA-107, miRNA-137 and miRNA-29b expression in meningiomas.