Neuroprotective effects of the new Na channel blocker rs100642 in global ischemic brain injury

KAMIŞLI, SUAT; Basaran, Cenk; BATÇIOĞLU, KADİR; ÖZTANIR, MUSTAFA; GÜL, MEHMET; SATILMIŞ, BASRİ; UYUMLU, AYŞE; KAYHAN, BAŞAK; Genc, Metin

doi:10.5114/aoms.2017.72550

Neuroprotective effects of the new Na channel blocker rs100642 in global ischemic brain injury

KAMIŞLI S., Basaran C., BATÇIOĞLU K., ÖZTANIR M. N., GÜL M., SATILMIŞ B., ...More

ARCHIVES OF MEDICAL SCIENCE, vol.15, no.2, pp.467-474, 2019 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 15 Issue: 2
Publication Date: 2019
Doi Number: 10.5114/aoms.2017.72550
Journal Name: ARCHIVES OF MEDICAL SCIENCE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.467-474
Open Archive Collection: AVESIS Open Access Collection
Bezmialem Vakıf University Affiliated: No

Abstract

Introduction: RS100642, a mexiletine analogue, is a novel sodium channel blocker with neuroprotective and antioxidant activities. The protectivity of RS100642, which has been shown against focal cerebral ischemia, was investigated in global cerebral ischemia in this study.