Neuroprotective effects of the new Na channel blocker rs100642 in global ischemic brain injury


KAMIŞLI S., Basaran C., BATÇIOĞLU K., ÖZTANIR M. N. , GÜL M., SATILMIŞ B., ...More

ARCHIVES OF MEDICAL SCIENCE, vol.15, no.2, pp.467-474, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.5114/aoms.2017.72550
  • Title of Journal : ARCHIVES OF MEDICAL SCIENCE
  • Page Numbers: pp.467-474

Abstract

Introduction: RS100642, a mexiletine analogue, is a novel sodium channel blocker with neuroprotective and antioxidant activities. The protectivity of RS100642, which has been shown against focal cerebral ischemia, was investigated in global cerebral ischemia in this study.