Neuroprotective effects of the new Na channel blocker rs100642 in global ischemic brain injury

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KAMIŞLI S., Basaran C., BATÇIOĞLU K., ÖZTANIR M. N., GÜL M., SATILMIŞ B., ...More

ARCHIVES OF MEDICAL SCIENCE, vol.15, no.2, pp.467-474, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.5114/aoms.2017.72550
  • Journal Name: ARCHIVES OF MEDICAL SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.467-474
  • Bezmialem Vakıf University Affiliated: No

Abstract

Introduction: RS100642, a mexiletine analogue, is a novel sodium channel blocker with neuroprotective and antioxidant activities. The protectivity of RS100642, which has been shown against focal cerebral ischemia, was investigated in global cerebral ischemia in this study.