Objective: The etiology of voiding dysfunction has garnered constant attention in the literature. Various factors such as UTI, bowel problems and constipation, negative attitudes of the social environment and the family, and genetics have been inspected and are still topics of investigation. UTI was found to have a strong association with pelvic wall dysfunction, constipation and lazy bowel syndrome, and voiding dysfunction. In this study we aimed to investigate the effects of urine pH and urine density studied in complete urinalysis on pediatric voiding dysfunction in order to contribute to the etiology of voiding dysfunction.
Method: A total of 43308 children were included in the study. Based on results of screening, 42196 children without voiding dysfunction were included in Group 1 and 1112 children with voiding dysfunction were assigned to Group 2. Results of complete urinalysis of all identified children were scanned to obtain urine pH and density values. Differences between the two groups in terms of independent parameters (urine pH and density) were analyzed using Student’s t-test. A p value<0.05 was considered statistically significant.
Results: The group with voiding dysfunction was determined to have a statistically significantly higher mean age. There was no difference between the groups in terms of urine pH values. However, urine density values were statistically significantly lower in the group with voiding dysfunction.
Conclusion: In general, children with voiding dysfunction are expected to have lower urine pH values, while urine density is not expected to show any differences. However, our study determined no differences in urine pH but detected lower urine density compared to the control group. Clearly, more advanced molecular or experimental prospective studies are required to explain this situation.
Keywords: Urine Dysfunction, Urine pH, Urine Density