Agents causing acute gastroenteritis are not common causes of pancreatitis etiology in children. Pancreatitis associated with rotavirus infection is very rare. Cases with acute pancreatitis during rotavirus gastroenteritis are reported due to rare associations. In this article, the causes of acute pancreatitis and cases of acute pancreatitis due to rotavirus infection were investigated. Clinical findings were mild, and complications were not observed in both of our patients, including a two-year-old female and a three-year-old male, and other cases evaluated in the literature. The patients were diagnosed with amylase-lipase elevation, imaging findings suggesting pancreatitis, and symptoms including vomiting and abdominal pain. The amylase and lipase levels of our patients decreased to normal levels in accordance with the literature, and no complication was observed in any patient. In the case of the continuation of abdominal pain in rotavirus gastroenteritis, it is essential to keep in mind the diagnosis of acute pancreatitis in terms of treatment and follow-up.