Circulating levels of cytokines are increased in restless legs syndrome

Uslu F. , Demir E., Güler E. M. , Koçyiğit A.

SLEEP AND BREATHING, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2020
  • Doi Number: 10.1007/s11325-020-02218-7
  • Title of Journal : SLEEP AND BREATHING
  • Keywords: Restless legs syndrome, Interleukin-6, Interleukin-1 beta, TNF-alpha, DISEASE, INTERLEUKIN-6, SLEEP, INFLAMMATION, ASSOCIATION


Background Restless legs syndrome [RLS] is known as a disease of iron and dopaminergic dysregulation but inflammatory processes might also have a role in the pathogenesis. In this study, we compared the circulating levels of hsCRP, IL-1 beta, IL-6, and TNF-alpha in patients with primary restless legs syndrome [RLS] and healthy control subjects.