Protective Effect of Pyrrolidine Dithiocarbamate on Myringosclerosis


Meric A. , Dogan R. , KAHYA V., Eren S. B. , YUKSEL M., Yegen G., ...Daha Fazla

JOURNAL OF INTERNATIONAL ADVANCED OTOLOGY, cilt.8, ss.223-230, 2012 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 8 Konu: 2
  • Basım Tarihi: 2012
  • Dergi Adı: JOURNAL OF INTERNATIONAL ADVANCED OTOLOGY
  • Sayfa Sayıları: ss.223-230

Özet

Objective: Myringotomy is most often used to treat recurrent acute otitis media and chronic effusion otitis media. The most common sequela of myringotomy is myringosclerosis. It has recently been shown that the development of myringosclerosis after myringotomy occurs concomitantly with an increased concentration of reactive oxygen species in the middle-ear cavity and an inflammatory reaction in the tympanic membrane. To assess the effect of pyrrolidine dithiocarbamate on acute inflammation due to myringotomy.