Türkiye Klinikleri Journal of Case Reports, cilt.33, sa.1, ss.27-30, 2025 (TRDizin)
ABSTRACT
Unilateral hypoglossal palsy, a rare condition causing one-sided tongue weakness or paralysis, often arises from medullary lesions but can also relate to other cranial nerve deficits from subarachnoid, skull base, or extracranial lesions. We report a rare case of isolated left hypoglossal nerve palsy due to left internal carotid artery (ICA) dissection. A woman in her 40s presented with dysphagia, dysarthria, and left-sided tongue weakness following a dental intervention. She experienced persistent headaches, which subsided over two weeks. Neurological examination revealed left tongue deviation and atrophy. Magnetic resonance angiography showed dissection of the distal cervical ICA with an intramural thrombus. The patient was treated with antiplatelet therapy and advised on physiotherapy for tongue and speech rehabilitation. At three-month follow-up, she showed recovery of tongue paresis and dysarthria. ICA dissection can cause isolated hypoglossal nerve palsy, highlighting the need to consider this diagnosis in cranial nerve palsy cases without trauma history.