Serum Irisin Levels in Central Precocious Puberty and Its Variants.

Kutlu E., Özgen İ. T., Bulut H., Koçyiğit A., Otçu H., Cesur Y.

The Journal of clinical endocrinology and metabolism, vol.106, no.1, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 106 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.1210/clinem/dgaa720
  • Journal Name: The Journal of clinical endocrinology and metabolism
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, BIOSIS, CAB Abstracts, Chemical Abstracts Core, CINAHL, EMBASE, Food Science & Technology Abstracts, Gender Studies Database, MEDLINE, Veterinary Science Database
  • Keywords: precocious puberty, premature thelarche, slowly progressing precocious puberty, irisin, adipomyokine, HUMAN CEREBROSPINAL-FLUID, PREMATURE THELARCHE, METABOLIC-CONTROL, OBESE CHILDREN, BODY-FAT, ADIPONECTIN, EXPRESSION, GIRLS, DIAGNOSIS, HORMONE
  • Bezmialem Vakıf University Affiliated: Yes


Aim: The exact mechanisms that trigger the onset of puberty are not well known. Adipomyokines are postulated to stimulate the central neural network. In the present study, we investigated irisin levels in girls with central precocious puberty (CPP), slowly progressing precocious puberty (SPPP), or premature thelarche (PT); we also studied prepubertal girls and to determine if this adipomyokine could be used as a marker in this context.