Acta Scientific Nutritional Health, vol.6, no.2, pp.103-111, 2022 (Peer-Reviewed Journal)
Summary: In the treatment of IBS patients, a holistic approach consisting of diet, lifestyle changes and drugs is required. Recent studies shown that vitamin D deficiency is common in IBS patients and supplementation of vitamin D can be effective in the treatment of IBS. The immunomodulatory, anti-inflammatory and antimicrobial properties of vitamin D and its association with psychosocial status are related to its role in IBS. Since IBS is a stress-sensitive disorder, impact of SARS-CoV-2 infection on IBS symptoms can not be ignored. In addition, IBS patients have a high risk of vitamin D deficiency resulting more severe symptoms during the pandemic. In this study, the role of vitamin D in IBS and the impact of SARS-CoV-2 infection in IBS patients were reviewed.
Key points: The intervention studies on vitamin D supplementation do not provide strong and generalizable evidence. SARS-CoV-2 infection could effect IBS symptoms. Vitamin D supplementation may be effective for IBS patients during COVID-19 pandemic since IBS patients are prone to infection and have a risk of more severe symptoms.
Keywords: Irritable Bowel Syndrome; Vitamin D; Vitamin D Deficiency; Microbiota; SARS-COV-2 Infection