Impact of surgical methodology on the complication rate and functional outcome of patients with a single brain metastasis

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PATEL A. J., SUKI D., Hatiboglu M. A., RAO V. Y., FOX B. D., SAWAYA R.

JOURNAL OF NEUROSURGERY, vol.122, no.5, pp.1132-1143, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 122 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.3171/2014.9.jns13939
  • Journal Name: JOURNAL OF NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1132-1143
  • Keywords: brain metastases, en bloc, craniotomy, complications, functional outcome, oncology, SOLID TUMOR-METASTASIS, POSTOPERATIVE RADIOTHERAPY, STEREOTACTIC RADIOSURGERY, PROGNOSTIC-FACTORS, CLINICAL ARTICLE, LOCAL RECURRENCE, COMPARATIVE RISK, NECK-SURGERY, MAJOR HEAD, RESECTION
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

OBJECT Brain metastases are the most common intracranial neoplasms and are on the increase. As radiation side effects are increasingly better understood, more patients are being treated with surgery alone with varying outcomes. The authors previously reported that en bloc resection of a single brain metastasis was associated with decreased incidences of leptomeningeal disease and local recurrence compared with piecemeal resection. However, en bloc resection is often feared to cause an increased incidence of postoperative complications. This study aimed to answer this question.