Relationship between fecal calprotectin level and disease activity in patients with hidradenitis suppurativa

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Eser E., Engin B., Yuksel P., Kocazeybek B. S., Kutlubay Z., Serdaroglu S., ...More

DERMATOLOGIC THERAPY, vol.33, no.2, 2020 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 33 Issue: 2
• Publication Date: 2020
• Doi Number: 10.1111/dth.13232
• Journal Name: DERMATOLOGIC THERAPY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
• Bezmialem Vakıf University Affiliated: Yes

Abstract

Background Hidradenitis suppurativa is a chronic, inflammatory, recurrent disease with recurrent abscesses, and sinus tract formation leading to scarring. Calprotectin has immunomodulatory, antimicrobial, and antiproliferative properties and is a calcium-binding protein primarily found in the neutrophil cytoplasm. In recent years, a significant relationship between the activity of various diseases and the level of calprotectin has led to the conclusion that there may be a similar relationship in hidradenitis suppurativa.