Anaphylaxis After the First Dose of Lansoprazole: A Case Report

EKİNCİ İ., KAYAR Y., DAE S. A., DUR A.

Meandros Medical and Dental Journal, vol.20, no.2, pp.179-181, 2019 (ESCI) identifier

  • Publication Type: Article / Case Report
  • Volume: 20 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.4274/meandros.galenos.2018.2550
  • Journal Name: Meandros Medical and Dental Journal
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.179-181
  • Keywords: Anaphylaxis, lansoprazole, proton pump inhibitors, drug allergy, CROSS-REACTIVITY, PROTON
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

Drug-induced anaphylaxis is a life-threatening condition that is rapid in onset and defined as a serious allergic or hypersensitivity reaction. Proton pump inhibitors are widely used for the treatment of acid-related disorders. These drugs are known as effective, safe and well tolerated. Although these drugs are known to be safe they may lead to life-threatening side effects such as anaphylaxis and interstitial lung disease in addition to minor side effects such as abdominal pain, headache, nausea, vomiting and diarrhea. A small number of anaphylactic reactions to lansoprazole have been described, although it is a commonly prescribed drug. We describe a case of anaphylaxis induced by oral intake of lansoprazole.