Myelofibrosis secondary to hyperparathyroidism


Kumbasar B., Taylan I., Kazancioglu R. , Agan M., Yenigun M., Sar F.

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, cilt.112, ss.127-130, 2004 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 112 Konu: 3
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1055/s-2004-817820
  • Dergi Adı: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
  • Sayfa Sayısı: ss.127-130

Özet

We report on a young female who had presented with fatigue, bilateral knee pain and gait disturbance. Primary hyperparathyroidism was diagnosed together with splenomegaly and anemia. Bone marrow biopsy revealed myelofibrosis. A parathyroid adenoma was excised during surgical intervention. As early as three months after the operation, hematologic parameters improved along with bone markers without any other intervention. The control bone marrow biopsy demonstrated well marked regression in marrow fibrosis. Her spleen has also gradually decreased in size.