Decreased nitrate-mediated dilatation in patients with coronary artery ectasia: an ultrasonographic evaluation of brachial artery


Aksoy Y., Acikgoz N. , Sivri N., Bariskaner E., Akturk E., Turhan H., ...More

CORONARY ARTERY DISEASE, vol.17, no.4, pp.365-369, 2006 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 4
  • Publication Date: 2006
  • Doi Number: 10.1097/00019501-200606000-00007
  • Title of Journal : CORONARY ARTERY DISEASE
  • Page Numbers: pp.365-369

Abstract

Background Coronary artery ectasia has been defined as localized or diffuse nonobstructive lesions of the epicardial coronary arteries With a luminal dilation exceeding the 1.5-fold of normal adjacent segment or vessel diameter. Although coronary artery disease is supposed to be responsible for more than 50% of coronary ectasia, the precise pathology of coronary artery ectasia is not clearly understood. The brachial artery ultrasound test for flow-mediated endothelial-dependent vasodilatory function includes administration of sublingual nitrates to examine the vasodilating effect of an exogenous source of nitric oxide. In the present study, we aimed to compare flow-mediated and nitrate-mediated responses of brachial artery in patients with coronary artery ectasia and patients with coronary artery disease.