Akademik Veri Yönetim Sistemi
Indian Journal of Pathology and Microbiology, cilt.67, sa.1, ss.226-229, 2024 (SCI-Expanded, Scopus)
Primary effusion lymphoma and its tissue‑based subtype extracavitary/solid variant was first described in human immunodeficiency virus (HIV)‑seropositive patients. We report the case of a 50‑year‑old HIV‑seronegative male patient who presented with icterus and cholestasis. Computed tomography revealed a 80 × 56 mm abdominal mass. Fine‑needle aspiration biopsy was performed from the celiac lymph nodes and pancreatic head, under endoscopic ultrasonography guidance. A duodenal endoscopic biopsy was taken from the infiltration area, and a core biopsy was performed for the portal hilar mass. All biopsies showed similar cytohistopathological features. LCA‑positive lymphoid neoplasia had a plasmacytoid/anaplastic morphology and null cell phenotype. HHV‑8 and Epstein‑Barr virus‑encoded small RNAs (EBER) were diffuse positive. The patient, who did not have an effusion, was diagnosed with an extracavitary/solid variant of primary effusion lymphoma. Virus‑associated lymphoproliferative disorders should be considered in the differential diagnosis of patients without a history of immunosuppression or HIV infection.