Inhibition of Amyloid β Aggregation Using Optimized Nano Encapsulated Formulations of Plant Extracts with High Metal Chelator Activities.

Kazdal F., Bahadori F., Celik B., Ertas A., Topcu G.

Current pharmaceutical biotechnology, cilt.21, ss.681-701, 2020 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21
  • Basım Tarihi: 2020
  • Doi Numarası: 10.2174/1389201021666191210125851
  • Dergi Adı: Current pharmaceutical biotechnology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, BIOSIS, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.681-701
  • Anahtar Kelimeler: Alzheimer, apo E4, metal chelator, nano-drug delivery, polyphenol, amyloid beta, ALZHEIMERS-DISEASE, ESSENTIAL OIL, FATTY-ACID, BIOLOGICAL-ACTIVITIES, A-BETA, GC-MS, ANTIOXIDANT, ANTICHOLINESTERASE, PROTEIN, PROFILE
  • Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

Background: The role of Fe+2, Cu+2 and Zn+2 in facilitating aggregation of Amyloid beta (A beta) and consequently, the progression of Alzheimer's disease (AD) is well established.