International journal of pediatric otorhinolaryngology, vol.78, no.4, pp.663-9, 2014 (Peer-Reviewed Journal)
Article / Article
International journal of pediatric otorhinolaryngology
Science Citation Index Expanded, Scopus
ABR, Amikacin, DPOAE, Oxidative status, Trimetazidine, TOTAL ANTIOXIDANT CAPACITY, INDUCED HEARING-LOSS, DOUBLE-BLIND, DAMAGE, GENTAMICIN, PREVENTION, AMINOGLYCOSIDES, REPERFUSION, ATTENUATION, RADICALS
Objective: Aminoglycoside antibiotics are known to have ototoxic effects and may induce sensorineural hearing loss. This study investigated the protective effect of trimetazidine, which has antioxidant and cytoprotective properties, against amikacin ototoxicity.