Protective effect of trimetazidine on amikacin-induced ototoxicity in rats.

AKSOY F. , Dogan R. , Ozturan O. , EREN S. B. , VEYSELLER B., PEKTAS A., ...Daha Fazla

International journal of pediatric otorhinolaryngology, cilt.78, ss.663-9, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 78 Konu: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.ijporl.2014.01.031
  • Dergi Adı: International journal of pediatric otorhinolaryngology
  • Sayfa Sayıları: ss.663-9

Özet

Objective: Aminoglycoside antibiotics are known to have ototoxic effects and may induce sensorineural hearing loss. This study investigated the protective effect of trimetazidine, which has antioxidant and cytoprotective properties, against amikacin ototoxicity.