Protective effect of trimetazidine on amikacin-induced ototoxicity in rats.


AKSOY F. , Dogan R. , Ozturan O. , EREN S. B. , VEYSELLER B., PEKTAS A., ...More

International journal of pediatric otorhinolaryngology, vol.78, no.4, pp.663-9, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 78 Issue: 4
  • Publication Date: 2014
  • Doi Number: 10.1016/j.ijporl.2014.01.031
  • Title of Journal : International journal of pediatric otorhinolaryngology
  • Page Numbers: pp.663-9

Abstract

Objective: Aminoglycoside antibiotics are known to have ototoxic effects and may induce sensorineural hearing loss. This study investigated the protective effect of trimetazidine, which has antioxidant and cytoprotective properties, against amikacin ototoxicity.