Protective effect of trimetazidine on amikacin-induced ototoxicity in rats.

AKSOY, FADLULLAH; Dogan, Remzi; Ozturan, ORHAN; EREN, SABRİ; VEYSELLER, Bayram; PEKTAS, Alev; HUSEYINBAS, Onder

doi:10.1016/j.ijporl.2014.01.031

Protective effect of trimetazidine on amikacin-induced ototoxicity in rats.

AKSOY F. , Dogan R. , Ozturan O. , EREN S. B. , VEYSELLER B., PEKTAS A., ...More

International journal of pediatric otorhinolaryngology, vol.78, no.4, pp.663-9, 2014 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 78 Issue: 4
Publication Date: 2014
Doi Number: 10.1016/j.ijporl.2014.01.031
Title of Journal : International journal of pediatric otorhinolaryngology
Page Numbers: pp.663-9

Abstract

Objective: Aminoglycoside antibiotics are known to have ototoxic effects and may induce sensorineural hearing loss. This study investigated the protective effect of trimetazidine, which has antioxidant and cytoprotective properties, against amikacin ototoxicity.