Anticholinesterase and Antioxidant Activities of Natural Abietane Diterpenoids with Molecular Docking Studies

TOPÇU G. , AKDEMİR A. , Kolak U., Ozturk M., Boga M., BAHADORİ F. , ...Daha Fazla

CURRENT ALZHEIMER RESEARCH, cilt.17, sa.3, ss.269-284, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Konu: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.2174/1567205017666200424133534
  • Dergi Adı: CURRENT ALZHEIMER RESEARCH
  • Sayfa Sayıları: ss.269-284

Özet

Background: Alzheimer's Disease (AD) is one of the most prevalent causes of dementia in the world, and no drugs available that can provide a complete cure. Cholinergic neurons of the cerebral cortex of AD patients are lost due to increased activity of cholinesterase enzymes.