Can ebselen prevent cisplatin-induced ovarian damage?

Soyman, Zeynep; Uzun, Hafize; Bayindir, NİHAN; EŞREFOĞLU, MUKADDES; Boran, Birtan

doi:10.1007/s00404-018-4750-4

Can ebselen prevent cisplatin-induced ovarian damage?

Soyman Z., Uzun H., Bayindir N. , EŞREFOĞLU M. , Boran B.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, vol.297, no.6, pp.1549-1555, 2018 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 297 Issue: 6
Publication Date: 2018
Doi Number: 10.1007/s00404-018-4750-4
Title of Journal : ARCHIVES OF GYNECOLOGY AND OBSTETRICS
Page Numbers: pp.1549-1555

Abstract

Purpose The occurrence of ovarian damage is a major shortcoming in treating tumors with cisplatin (CP). The present study investigates the beneficial effects of ebselen-a seleno-organic compound with antioxidant and antiinflammatory properties-vis-a-vis CP-induced ovarian damage.