Can ebselen prevent cisplatin-induced ovarian damage?

Soyman Z., Uzun H., Bayindir N. , EŞREFOĞLU M. , Boran B.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, cilt.297, sa.6, ss.1549-1555, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 297 Konu: 6
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1007/s00404-018-4750-4
  • Dergi Adı: ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • Sayfa Sayıları: ss.1549-1555

Özet

Purpose The occurrence of ovarian damage is a major shortcoming in treating tumors with cisplatin (CP). The present study investigates the beneficial effects of ebselen-a seleno-organic compound with antioxidant and antiinflammatory properties-vis-a-vis CP-induced ovarian damage.