Can ebselen prevent cisplatin-induced ovarian damage?

Soyman, Zeynep; Uzun, Hafize; Bayindir, NİHAN; EŞREFOĞLU, MUKADDES; Boran, Birtan

doi:10.1007/s00404-018-4750-4

Can ebselen prevent cisplatin-induced ovarian damage?

Atıf İçin Kopyala

Soyman Z., Uzun H., Bayindir N. , EŞREFOĞLU M. , Boran B.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, cilt.297, ss.1549-1555, 2018 (SCI İndekslerine Giren Dergi)

Cilt numarası: 297 Konu: 6
Basım Tarihi: 2018
Doi Numarası: 10.1007/s00404-018-4750-4
Dergi Adı: ARCHIVES OF GYNECOLOGY AND OBSTETRICS
Sayfa Sayısı: ss.1549-1555

Özet

Purpose The occurrence of ovarian damage is a major shortcoming in treating tumors with cisplatin (CP). The present study investigates the beneficial effects of ebselen-a seleno-organic compound with antioxidant and antiinflammatory properties-vis-a-vis CP-induced ovarian damage.