DNA damage and oxidative status in PFAPA syndrome.


TUGRUL S., Dogan R., Kocyigit A., Torun E., SENTURK E., Ozturan O.

Auris, nasus, larynx, vol.42, no.5, pp.406-11, 2015 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.1016/j.anl.2015.03.007
  • Journal Name: Auris, nasus, larynx
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.406-11
  • Keywords: DNA damage, Oxidative status, PFAPA, PERIODIC FEVER, APHTHOUS STOMATITIS, ADENITIS PFAPA, PHARYNGITIS, STRESS, ACTIVATION, DIAGNOSIS, DISORDER

Abstract

Objective: PFAPA syndrome is a clinical entity of unknown etiology which presents with periodic episodes of fever, aphthous stomatitis, tonsillitis or pharyngitis, and cervical adenitis. In this study we investigated DNA damage and the oxidative stress parameters in patients diagnosed with PFAPA, to elucidate the underlying pathophysiological mechanism of this syndrome.