Sambulin A and B, non-glycosidic iridoids from Sambucus ebulus, exert significant in vitro anti-inflammatory activity in LPS-induced RAW 264.7 macrophages via inhibition of MAPKs's phosphorylation

Balkan I. A. , Akulke A. Z. I. , Bagatur Y., Telci D., Goren A. C. , Kirmizibekmez H., ...Daha Fazla

JOURNAL OF ETHNOPHARMACOLOGY, cilt.206, ss.347-352, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 206
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.jep.2017.06.002
  • Sayfa Sayıları: ss.347-352


Ethnopharmacological relevance: The leaves of Sambucus ebulus L. (Adoxaceae) are widely used in Turkish folk medicine particularly against inflammatory disorders. The fresh leaves after wilted over fire or the poultices prepared are directly applied externally to heal burns, edema, eczema, urticarial and abscess. Two iridoids were recently isolated (sambulin A, sambulin B) from the leaves of S. ebulus.