Sambulin A and B, non-glycosidic iridoids from Sambucus ebulus, exert significant in vitro anti-inflammatory activity in LPS-induced RAW 264.7 macrophages via inhibition of MAPKs's phosphorylation


Balkan I. A. , Akulke A. Z. I. , Bagatur Y., Telci D., Goren A. C. , Kirmizibekmez H., et al.

JOURNAL OF ETHNOPHARMACOLOGY, cilt.206, ss.347-352, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 206
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.jep.2017.06.002
  • Dergi Adı: JOURNAL OF ETHNOPHARMACOLOGY
  • Sayfa Sayısı: ss.347-352

Özet

Ethnopharmacological relevance: The leaves of Sambucus ebulus L. (Adoxaceae) are widely used in Turkish folk medicine particularly against inflammatory disorders. The fresh leaves after wilted over fire or the poultices prepared are directly applied externally to heal burns, edema, eczema, urticarial and abscess. Two iridoids were recently isolated (sambulin A, sambulin B) from the leaves of S. ebulus.