PEERJ, vol.7, 2020 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals
H5N1, Influenza virus, Sequence diversity, Variants, Fitness-selection, Dynamics, EPIDEMIOLOGY, CONSERVATION, VARIABILITY, GENERATION, RESPONSES, VACCINES
Bezmialem Vakıf University Affiliated:
Background. InfluenzaA(H5N1) virus is a global concern with potential as a pandemic threat. High sequence variability of influenza A viruses is a major challenge for effective vaccine design. A continuing goal towards this is a greater understanding of influenza A (H5N1) proteome sequence diversity in the context of the immune system (antigenic diversity), the dynamics of mutation, and effective strategies to overcome the diversity for vaccine design.