Genomic landscape of the Greater Middle East

Ozcelik T., ONAT O. E.

NATURE GENETICS, no.9, pp.978-979, 2016 (SCI-Expanded, Scopus) identifier

  • Publication Type: Article / Editorial Material
  • Publication Date: 2016
  • Doi Number: 10.1038/ng.3652
  • Journal Name: NATURE GENETICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.978-979
  • Bezmialem Vakıf University Affiliated: No

Abstract

Study of the Greater Middle East (GME), home to approximately 10% of the world's population, has made invaluable contributions to the characterization of rare genetic disease, especially recessive conditions arising from the tradition of consanguinity and large families with multiple children. A new study now reports 1,111 unrelated exomes from the GME and provides a comprehensive view of genetic variation for enhanced discovery of disease-associated genes.