Investigation of Diagnostic Proteins by 2D Electrophoresis in Major Depression Model Induced by Forced Swim Test in Rats

Duman T., Akyüz E., Bulut H., Koçyiğit A., Tülek A., KarataŞ E., ...Daha Fazla

PROTEIN AND PEPTIDE LETTERS, cilt.28, sa.2, ss.195-204, 2021 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2174/0929866527999200729183729
  • Dergi Adı: PROTEIN AND PEPTIDE LETTERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.195-204
  • Anahtar Kelimeler: Depression model, rats, 2D electrophoresis, protein, forcing swim test, major depression
  • Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

Background: Aside from its pervasiveness, whereby it affects as much as 20% of the world's population, depression continues to be one of the most crucial psychiatric problems due to the loss of power it causes by disrupting daily life functioning, containing economic consequences, and having a high suicidal tendency. Major depression (MD) is a systemic and multifactorial disorder involving complex interactions between genetic predisposition and disturbances of various molecular pathways.