Analysis of Chromosome 3, 7 and 8 Centromeric Regions in Bronchial Lavage Specimens by FISH


Atasoy S. , Erturan S. S. , Yilmaz N., Kuru D., Cirakoglu A., Yilmaz S., et al.

TURKISH THORACIC JOURNAL, cilt.17, ss.141-147, 2016 (ESCI İndekslerine Giren Dergi)

  • Cilt numarası: 17 Konu: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5578/ttj.30506
  • Dergi Adı: TURKISH THORACIC JOURNAL
  • Sayfa Sayısı: ss.141-147

Özet

OBJECTIVES: Multiple genetic changes are observed in malignant tumors but are rare or absent in benign conditions. Aneuploidy is the most common feature of solid tumors including lung cancer and diagnosis of malignant tumors is possible through detection of aneuploidy. The aim of this study was to investigate chromosomal abnormalities in cells from non-small cell lung cancer patients obtained bronchoscopically and to evaluate the suitability of fluorescence in situ hybridization (FISH).