The Influence of Gender and Age on Laparoscopic Sleeve Gastrectomy Short-Term Outcomes in Type-2 Diabetic Obese Patients

Elbasan O., Şişman P., Peynirci H., Yabacı A., Ersoy C.

Turkish Journal of Internal Medicine, pp.1-8, 2021 (Peer-Reviewed Journal)


Background Bariatric surgery has come out as an effective treatment for morbid obesity due to its effects as stabilized weight loss and remission of obesity related comorbidities like type 2 diabetes. Postoperative weight loss is affected by many factors and predictors of weight loss after bariatric surgery are controversial.This study has been performed to evaluate the impact of gender and age on the shortterm outcomes of laparoscopic sleeve gastrectomy (LSG) in type 2 diabetic(T2D) obese patients. Material and Methods In this retrospective study,the records of morbidly obese patients with a body mass index(BMI)≥40 kg/m2,aged between 18-65 years old who underwent LSG and were followed-up for at least 6 months postoperatively were reviewed.Patients were subdivided into two groups according to age(≥50 y,<50 y),gender(female, male) and compared. Results The study included 25 patients, 17(68%) female and 8(32%) male, 14(56%) were in <50 years old group and 11(44%) were in ≥50 years old group.At the postoperative 6th month,there was a significant decrease in weight,BMI,diastolic blood pressure,fasting blood glucose,postprandial glucose and HbA1c in both gender and age groups (p<0.05).A significant decrease was observed in Triglyceride(TG) at 6th month in both gender.While a significant increase in High-density Lipoprotein (HDL) was observed in patients aged ≥50 (p=0.028),no significant change was observed in the younger group.There was a positive correlation between change in Total Cholesterol(TCh),TG and age (respectively;r=0.436,p=0.030, r=0.528,p=0.007). Conclusions LSG is an effective treatment method for morbid obesity for younger(<50 y) and advanced aged(≥50 y) T2D patients in both genders. The percentage changes in the decreament of TG in male gender and TCh in younger age were more prominent in short-term follow-up