Elevated chemokine levels during adult but not pediatric Crimean-Congo hemorrhagic fever

Arasli, Mehmet; ÖZSÜREKCİ, YASEMİN; ELALDI, NAZİF; MCAULEY, Alexander; Oncel, Eda; Tekin, Ishak; GÖZEL, MUSTAFA; KAYA, ALİ; İÇAĞASIOĞLU, DİLARA; CAGLAYIK, Dilek; KORUKLUOGLU, Gulay; Kokturk, Furuzan; Bakir, Mehmet; BENTE, Dennis; Ceyhan, Mehmet

doi:10.1016/j.jcv.2015.03.010

Elevated chemokine levels during adult but not pediatric Crimean-Congo hemorrhagic fever

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Arasli M., ÖZSÜREKCİ Y., ELALDI N., MCAULEY A. J., Oncel E. K., Tekin I. O., ...More

JOURNAL OF CLINICAL VIROLOGY, vol.66, pp.76-82, 2015 (SCI-Expanded)

Publication Type: Article / Article
Volume: 66
Publication Date: 2015
Doi Number: 10.1016/j.jcv.2015.03.010
Journal Name: JOURNAL OF CLINICAL VIROLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.76-82
Keywords: Crimean-Congo hemorrhagic fever, Chemokine, Adults, Children, INFLAMMATORY RESPONSE, VIRUS-INFECTION, VIRAL LOAD, PATHOGENESIS, CELLS, CHILDREN, DEFENSE, MOUSE
Bezmialem Vakıf University Affiliated: No

Abstract

Background: Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral zoonosis. Clinical reports indicate the severity of CCHF is milder in children than adults. The chemokines are important chemoattractant mediators of the host immune system.