Carbontetrachloride induced acute liver damage and protective effect of n-acetylcysteine on rats with regenerated and non-regenerated liver


Bilgic S., ÖZEROL E., Iraz M., Sahin N. , TANBEK K., ÇIĞLI A.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.41, ss.189-197, 2016 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 41 Konu: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1515/tjb-2016-0029
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Sayfa Sayısı: ss.189-197

Özet

Objective: Our aim was to investigate 70% partial hepatectomy (PH) groups, compare with not subjected to PH groups after exposure to hepatotoxic agents for alterations in the protective effects of antioxidant agents and sensitivity of the liver. Accordingly, we aimed to investigate the toxicity of a hepatotoxic agent, carbon tetrachloride (CCl4), and protective effects of an antioxidant, N-acetylcysteine (NAC), in experimental animal model.