Antioxidant and anti-inflammatory effects of curcumin against hepatorenal oxidative injury in an experimental sepsis model in rats


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SAVCUN G. Y. , OZKAN E., DULUNDU E., TOPALOGLU U., Sehirli A. O. , Tok O. E. , et al.

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, cilt.19, ss.507-515, 2013 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 19 Konu: 6
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5505/tjtes.2013.76390
  • Dergi Adı: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
  • Sayfa Sayısı: ss.507-515

Özet

BACKGROUND: To investigate the effects of curcumin, an antioxidant and anti-inflammatory agent, on free oxygen radicals and lipid peroxidation in an experimental sepsis model, as well as to determine the role of curcumin in preventing hepatorenal tissue damage caused by sepsis.