Antioxidant and anti-inflammatory effects of curcumin against hepatorenal oxidative injury in an experimental sepsis model in rats

SAVCUN, Gulay; OZKAN, Erkan; DULUNDU, ENDER; TOPALOGLU, Umit; Sehirli, Ahmet; Tok, OLGU; ERCAN, FERİHA; ŞENER, GÖKSEL

doi:10.5505/tjtes.2013.76390

Antioxidant and anti-inflammatory effects of curcumin against hepatorenal oxidative injury in an experimental sepsis model in rats

SAVCUN G. Y., OZKAN E., DULUNDU E., TOPALOGLU U., Sehirli A. O., Tok O. E., ...More

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, vol.19, no.6, pp.507-515, 2013 (SCI-Expanded)

Publication Type: Article / Article
Volume: 19 Issue: 6
Publication Date: 2013
Doi Number: 10.5505/tjtes.2013.76390
Journal Name: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Page Numbers: pp.507-515
Bezmialem Vakıf University Affiliated: No

Abstract

BACKGROUND: To investigate the effects of curcumin, an antioxidant and anti-inflammatory agent, on free oxygen radicals and lipid peroxidation in an experimental sepsis model, as well as to determine the role of curcumin in preventing hepatorenal tissue damage caused by sepsis.