Synthesis of gamma-glutamyl beta-cyanoalanine precursor

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Un S. S., Altundas R., GÖREN A. C.

ORGANIC COMMUNICATIONS, vol.13, no.4, pp.202-206, 2020 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.25135/acg.oc.89.20.05.1660
  • Journal Name: ORGANIC COMMUNICATIONS
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.202-206
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

The synthesis of precursors of neurotoxic gamma-glutamyl beta-cyanoalanine was developed starting from L-Serine via through the preparation of beta-cyanoalanine and glutamyl units. Coupling of these two intermediates gave methyl ester of gamma-glutamyl beta-cyanoalanine precursor. (C) 2020 ACG Publications. All rights reserved.