Akademik Veri Yönetim Sistemi
6th International "Artemis" Congress on Health and Sports Sciences, İzmir, Türkiye, 26 - 27 Mart 2024, ss.23-24, (Özet Bildiri)
In recent studies, it has been
noticed that vitamin D is beneficial for many processes that negatively affect
body homeostasis, especially cardiovascular diseases, diabetes, metabolic
syndrome, stroke, autoimmune disorders, neurocognitive disorders and body
homeostasis. Although these effects of vitamin D on the cardiovascular system
may be mediated through the endocrine system, or through mechanisms formed by
many complex compounds, or through the gene transcription pattern described in
tissues, research has been shown to be abundant with some uncertainty. As a
result of the experiments, it is aimed to give information about how the
negative cardiac effects progress to myocardial infarction and the mechanisms
by which this may occur. By affecting the vascular endothelial mechanism, it
leads to ischemic conditions such as atherosclerosis. Then it causes a
myocardial infarction. If it goes forward, it creates conditions such as heart
failure. The inhibitory effect of vitamin D is explained by gene rotations. The
importance of the vitamin's relationship with immune cells and its pleitropic
effects on the renin-angiotensin-aldosterone model are also explained. Clinical
studies have shown that cardiovascular health is negatively affected in people
with serum vitamin D hypovitamin deficiency, and myocardial infarction occurs
when ischemic heart disease, which causes the most mortality, becomes chronic. Apart
from the effect of active form of vitamin D1,25(OH)2D3 on osteocytes and
osteoblast cells, its effect on these systems is positive. In this review
study, vitamin D itself and the mechanisms by which it can prevent myocardial
infarction by protecting cardiovascular health will be presented along with
studies. The need for more studies is also included here with conflicting
views.
Keywords: Vitamin
D, myocardial infarction, heart failure