Serum obestatin and omentin levels in patients with diabetic nephropathy

ZORLU M., KISKAC M., Gueler E. M., GUELTEPE I., YAVUZ E., CELIK K., ...Daha Fazla

NIGERIAN JOURNAL OF CLINICAL PRACTICE, cilt.20, sa.2, ss.182-187, 2017 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4103/1119-3077.181350
  • Dergi Adı: NIGERIAN JOURNAL OF CLINICAL PRACTICE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.182-187
  • Anahtar Kelimeler: Diabetes mellitus type 2, diabetic nephropathy, obestatin, omentin, GHRELIN/OBESTATIN RATIO, CIRCULATING OMENTIN, INSULIN-RESISTANCE, METABOLIC SYNDROME, PLASMA OBESTATIN, GHRELIN, INFLAMMATION, MICROALBUMINURIA, ASSOCIATION, BIOMARKER
  • Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

Introduction: Diabetic nephropathy is the leading cause of chronic kidney disease and accounts for almost 45% of all new patients requiring renal replacement therapy. Omentin and obestatin, two novel proteins were suggested to be associated with insulin resistance, type 2 diabetes and cardiovascular risk factors. Thus, we postulated that they may also have an association with diabetic nephropathy which is known to be an independent cardiovascular risk factor. In order to investigate such an association we compared serum omentin and obestatin levels in type 2 diabetic patients with normoalbuminuria (NA) and macroalbuminuria (MA).