Cytotoxicity of a new antimicrobial coating for surgical screws: an in vivo study

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Guzel Y., Elmadag M. , Uzer G. , Yildiz F. , Bilsel K. , Tuncay I.

SINGAPORE MEDICAL JOURNAL, vol.58, no.1, pp.46-49, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 58 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.11622/smedj.2016021
  • Page Numbers: pp.46-49


INTRODUCTION The risk of surgery-related infection is a persistent problem in orthopaedics and infections involving implants are particularly difficult to treat. This study explored the responses of bone and soft tissue to antimicrobial-coated screws. We investigated whether such screws, which have never been used to fix bony tissues, would result in a cytotoxic effect. We hypothesised that the coated screws would not be toxic to the bone and that the likelihood of infection would be reduced since bacteria are not able to grow on these screws.