Cander B., Taşlıdere B., Sönmez E.
9Th International Critical Care And Emergency Medicine Congress, Ekim 2022
-
Ödülün Kapsamı:
Bilimsel/Mesleki Çalışmalardan Alınan Ödül
-
Ödül Türü:
Kongre, Konferans, Festival veya Sempozyum Kurullarınca Verilen Ödül
-
Ödül Veren Ülke:
Türkiye
-
Ödülü Veren Organizasyon:
9Th International Critical Care And Emergency Medicine Congress
-
Araştırma Alanları:
Tıp, Cerrahi Tıp Bilimleri, Acil Tıp, Sağlık Bilimleri
-
Ödülün Tarihi:
Ekim 2022
-
Açıklama:
<p>OBJECTIVE: Chest pain constitutes a significant portion of all emergency department admissions. Approximately 5%–20% of patients who enter the emergency department with chest pain
are diagnosed with acute coronary syndrome. A reliable predictor is needed for ACS patients with high mortality risk. Therefore, we investigated its contribution to prognostic accuracy by
adding cTnI concentration (as a fourth parameter) to the qSOFA score. The precision of the qSOFA-T score obtained by adding Troponin to the qSOFA score has never been investigated in
any previous study. This study aimed to evaluate the effectiveness of the GRACE score and qSOFA-T score for in-hospital mortality estimation in ACS Patients (1,2)
METHODS: Patients admitted to the emergency department with acute coronary syndrome were evaluated consecutively. After the exclusion criteria, 914 patients with non-STEMI were
included in the study. The GRACE and qSOFA scores were calculated and investigated its contribution to prognostic accuracy by adding cTnI concentration to the qSOFA score. This is an
observational and retrospective study. The threshold value of the investigated prognostic markers was calculated by receiver operating characteristic curve analysis.
RESULTS: Of the 914 patients, 628 (68.7%) were male. The mean age was 52.95 years. The number of in-hospital deaths was 31 (3.4%). The mean GRACE score in the in-hospital deceased
group was 149.77. In the survivor group, it was found to be 103.3. The mean qSOFA-T score for the in-hospital-deaths group was 2.03. It was calculated as 1.09 for the survivor group. In
our study, the area under the ROC curve was 0.840 and the cut-off value was 139.5. The area under the ROC curve was found to be 0.826, with a cut-off value of 1.5.
CONCLUSION: The qSOFA-T score, obtained by adding cTnI level to the qSOFA score, had excellent discriminatory power for predicting in-hospital mortality. The AUC of the GRACE scorewas 0.840, and the AUC of the qSOFA-T score was 0.826; both scores had excellent discriminatory power for predicting in-hospital mortality. (0.8 <= AUC <0.9, an excellent). In estimating
the qSOFA-T score as a predictor of in-hospital mortality, the cut-off value was 1.5, and the mean value was 2.03. Care should be taken if the calculated qSOFA-T score is two or higher. This
study concludes that patients with a high qSOFA-T score, which can be calculated easily, quickly, and inexpensively, are at a higher risk of short-term Mortality (3-5).
</p><p>KEYWORDS: Acute coronary syndrome, cTnI, GRACE score, Mortalit<br></p>